Title : The core promoter region of the tumor necrosis factor alpha gene confers phorbol ester responsiveness to upstream transcriptional activators.

Pub. Date : 1992 Mar

PMID : 1545816






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The proximal TNF promoter containing only 28 nucleotides upstream and 10 nucleotides downstream of the RNA start site confers TPA activation to a variety of unrelated upstream enhancer elements and transcription factors, including Sp1, CTF/NF1, cyclic AMP-response element, GAL-E1a, and GAL-VP16. Tetradecanoylphorbol Acetate nuclear factor I C Homo sapiens