Title : Optimal windows of statin use for immediate infarct limitation: 5'-nucleotidase as another downstream molecule of phosphatidylinositol 3-kinase.

Pub. Date : 2004 Oct 12

PMID : 15451788






2 Functional Relationships(s)
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1 In all cases, both Akt and ecto-5"-nucleotidase showed activation in parallel, and this activation was completely abolished by wortmannin, a PI3-K inhibitor. Wortmannin 5'-nucleotidase ecto Canis lupus familiaris
2 The magnitude of the infarct-limiting effect paralleled the increase in Akt and ecto-5"-nucleotidase activity and was blunted by administration of wortmannin, alpha,beta-methyleneadenosine-5"-diphosphate, or 8-sulfophenyltheophylline during reperfusion. Wortmannin 5'-nucleotidase ecto Canis lupus familiaris