Title : Cultured fibroblasts from patients with Niemann-Pick disease type C and type D exhibit distinct defects in cholesterol esterification.

Pub. Date : 1992 Feb 20

PMID : 1543723






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In contrast, cholesterol esterification in NPD fibroblasts increased slowly during the first 6-12 h and reached 50% of normal values by 24 h. 25-Hydroxycholesterol, a non-lipoprotein stimulator of cholesterol esterification, caused a similar stimulation of cholesterol esterification in NPC, NPD and normal cells. Hydroxycholesterols NPC intracellular cholesterol transporter 1 Homo sapiens