Title : Stabilization of alanine substituted p53 protein at Ser15, Thr18, and Ser20 in response to ionizing radiation.

Pub. Date : 2004 Oct 22

PMID : 15381086






3 Functional Relationships(s)
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1 Stabilization of alanine substituted p53 protein at Ser15, Thr18, and Ser20 in response to ionizing radiation. Alanine tumor protein p53 Homo sapiens
2 In the present study, we examined the X-ray-induced stabilization of Ala-substituted p53 protein at Ser15, Thr18, and Ser20, whose gene expression was controlled under an ecdyson-inducible promoter. Alanine tumor protein p53 Homo sapiens
3 We found that all single-, double-, or triple-Ala-substituted p53 at Ser15, Yhr18, and Ser20 were accumulated in the nucleus similarly to wild-type p53 after X-irradiation. Alanine tumor protein p53 Homo sapiens