Title : Beta4 integrin is involved in statin-induced endothelial cell death.

Pub. Date : 2004 Oct 22

PMID : 15381079






1 Functional Relationships(s)
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1 The endothelial death and beta4 integrin upregulation by ATV could be reversed by intermediate metabilites of the HMG-CoA reductase pathway mevalonate or GGPP, but not by FPP, suggesting that these effects were results of specific inhibition of the pathway. Atorvastatin 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens