Pub. Date : 2004 Nov
PMID : 15375300
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Rho negatively regulates endothelial nitric oxide synthase and Rac contributes to NAD(P)H-oxidase activation and superoxide production. | Superoxides | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Statins inhibit both Rho and Rac GTPase activity via inhibition of geranylgeranylation, which confers endothelial nitric oxide synthase upregulation and decreases superoxide production, respectively. | Superoxides | AKT serine/threonine kinase 1 | Homo sapiens |