Title : The effects of gender, age, ethnicity, and liver cirrhosis on cytochrome P450 enzyme activity in human liver microsomes and inducibility in cultured human hepatocytes.

Pub. Date : 2004 Sep 15

PMID : 15364537






1 Functional Relationships(s)
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1 Primary cultures of hepatocytes were treated with beta-naphthoflavone, an inducer of CYP1A2, phenobarbital or rifampin, both of which induce CYP2B6, CYP2C9, CYP2C19, and CYP3A4, albeit it to different extents. Rifampin cytochrome P450 family 2 subfamily B member 6 Homo sapiens