Title : Polyamine-modulated expression of c-myc plays a critical role in stimulation of normal intestinal epithelial cell proliferation.

Pub. Date : 2005 Jan

PMID : 15355849






2 Functional Relationships(s)
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1 Disruption of c-myc expression using specific c-myc antisense oligomers not only inhibited normal cell growth (without DFMO) but also prevented the restoration of cell proliferation by spermidine in polyamine-deficient cells. Spermidine MYC proto-oncogene, bHLH transcription factor Homo sapiens
2 Disruption of c-myc expression using specific c-myc antisense oligomers not only inhibited normal cell growth (without DFMO) but also prevented the restoration of cell proliferation by spermidine in polyamine-deficient cells. Spermidine MYC proto-oncogene, bHLH transcription factor Homo sapiens