Title : Mutation in saposin D domain of sphingolipid activator protein gene causes urinary system defects and cerebellar Purkinje cell degeneration with accumulation of hydroxy fatty acid-containing ceramide in mouse.

Pub. Date : 2004 Nov 1

PMID : 15345707






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The sphingolipid activator proteins (saposins A, B, C and D) are small homologous glycoproteins that are encoded by a single gene in tandem within a large precursor protein (prosaposin) and are required for in vivo degradation of some sphingolipids with relatively short carbohydrate chains. Sphingolipids prosaposin Mus musculus