Title : Anti-apoptotic action of (2S,3S,4R)-N"-cyano-N-(6-amino-3,4-dihydro-3-hydroxy-2-methyl-2-dimethoxymethyl-2H-benzopyran-4-yl)-N'-benzylguanidine (KR-31378) by suppression of the phosphatase and tensin homolog deleted from chromosome 10 phosphorylation and increased phosphorylation of casein kinase2/Akt/ cyclic AMP response element binding protein via maxi-K channel opening in neuronal cells.

Pub. Date : 2004 Aug 30

PMID : 15336944






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 KR-31378 restored TNF-alpha-induced decreased cell viability of SK-N-SH. sk-n-sh tumor necrosis factor Homo sapiens