Title : Ser/Thr protein phosphatase 5 inactivates hypoxia-induced activation of an apoptosis signal-regulating kinase 1/MKK-4/JNK signaling cascade.

Pub. Date : 2004 Nov 5

PMID : 15328343






1 Functional Relationships(s)
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1 Together, these studies indicate that PP5 plays an important role in the survival of cells in a low oxygen environment by suppressing a hypoxia-induced ASK-1/MKK4/JNK signaling cascade that promotes an apoptotic response. Oxygen mitogen-activated protein kinase kinase kinase 5 Homo sapiens