Title : Alterations in cellular phenotype induced by the type 5 adenovirus E1A and the beta 1 protein kinase C genes in cloned rat embryo fibroblast cells.

Pub. Date : 1992 Feb

PMID : 1532767






2 Functional Relationships(s)
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1 In Ad5 E1A and Ad5 E1A + low-level beta 1 PKC expressing CREF clones, the tumor promoting agent 12-0-tetradecanoyl-phorbol-13-acetate (TPA) further enhances anchorage-independence. Tetradecanoylphorbol Acetate branched chain keto acid dehydrogenase E1 subunit alpha Rattus norvegicus
2 In addition, the combination of a transfected Ad5 E1A and a beta 1 PKC gene in the same CREF clone results in an enhanced expression of the transformed phenotype in both the absence and presence of TPA. Tetradecanoylphorbol Acetate branched chain keto acid dehydrogenase E1 subunit alpha Rattus norvegicus