Pub. Date : 1992 Feb 19
PMID : 1531148
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | BACKGROUND: Fewer than 20% of patients with nonhematologic malignancies treated with chloroethylnitrosoureas (CENUs) respond, but streptozocin (STZ), which depletes O6-methylguanine-DNA-methyltransferase (MGMT), has been shown to reverse resistance to CENUs in vitro. | 1-(2-chloroethyl)-1-nitrosourea | O-6-methylguanine-DNA methyltransferase | Homo sapiens |
2 | BACKGROUND: Fewer than 20% of patients with nonhematologic malignancies treated with chloroethylnitrosoureas (CENUs) respond, but streptozocin (STZ), which depletes O6-methylguanine-DNA-methyltransferase (MGMT), has been shown to reverse resistance to CENUs in vitro. | 1-(2-chloroethyl)-1-nitrosourea | O-6-methylguanine-DNA methyltransferase | Homo sapiens |
3 | BACKGROUND: Fewer than 20% of patients with nonhematologic malignancies treated with chloroethylnitrosoureas (CENUs) respond, but streptozocin (STZ), which depletes O6-methylguanine-DNA-methyltransferase (MGMT), has been shown to reverse resistance to CENUs in vitro. | 1-(2-chloroethyl)-1-nitrosourea | O-6-methylguanine-DNA methyltransferase | Homo sapiens |