Pub. Date : 2004 Aug 23
PMID : 15306127
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effects of the selective norepinephrine uptake inhibitor nisoxetine on prodynorphin gene expression in rat CNS. | nisoxetine | prodynorphin | Rattus norvegicus |
| 2 | The effect of the selective norepinephrine uptake inhibitor nisoxetine was examined on PDYN gene expression. | nisoxetine | prodynorphin | Rattus norvegicus |
| 3 | These data suggest that nisoxetine affects PDYN gene expression and support a role for NE in the mechanisms underlying the effects of chronic exposure to psychoactive drugs. | nisoxetine | prodynorphin | Rattus norvegicus |
| 4 | Moreover, nisoxetine, as well as fluoxetine, decreases PDYN mRNA in the caudate putamen, in contrast to the up-regulation produced by cocaine. | nisoxetine | prodynorphin | Rattus norvegicus |