Pub. Date : 2004 Sep 1
PMID : 15304524
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Our results indicate that the class-I Rab11-FIPs bind preferentially to phosphatidylinositol-(3,4,5)-trisphosphate [PtdIns(3,4,5)P3] and the second messenger phosphatidic acid. | Phosphatidic Acids | RAB11A, member RAS oncogene family | Homo sapiens |
| 2 | Stimulation of PtdIns(3,4,5)P3 or phosphatidic acid synthesis results in the translocation of the Rab11-FIPs from a perinuclear location to the periphery of the cell. | Phosphatidic Acids | RAB11A, member RAS oncogene family | Homo sapiens |
| 3 | We propose that the C2 domains of the class I Rab11-FIPs function to target these proteins to "docking sites" in the plasma membrane that are enriched in PtdIns(3,4,5)P3 and phosphatidic acid. | Phosphatidic Acids | RAB11A, member RAS oncogene family | Homo sapiens |