Title : Aluminum hydroxide adjuvant induces macrophage differentiation towards a specialized antigen-presenting cell type.

Pub. Date : 2004 Aug 13

PMID : 15297065






1 Functional Relationships(s)
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1 AlOOH-loaded macrophages exhibited phenotypical and functional modifications, as they expressed the classical markers of myeloid dendritic cells (HLA-DR(high)/CD86(high)/CD83(+)/CD1a(-)/CD14(-)) and displayed potent ability to induce MHC-II-restricted antigen specific memory responses, but kept a macrophage morphology. aluminum oxide hydroxide CD86 molecule Homo sapiens