Title : Resistance to purine and pyrimidine nucleoside and nucleobase analogs by the human MDR1 transfected murine leukemia cell line L1210/VMDRC.06.

Pub. Date : 2004 Sep 1

PMID : 15294454






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Overexpression of human MDR1 P-glycoprotein [Pgp] is associated with cellular resistance to bulky amphipathic drugs, such as taxol, anthracyclines, vinca alkaloids, and epipodophyllotoxins by actively effluxing drugs from cells. Anthracyclines phosphoglycolate phosphatase Homo sapiens