Title : The effects of lycopene on the proliferation of human breast cells and BRCA1 and BRCA2 gene expression.

Pub. Date : 2004 Jul

PMID : 15251168






2 Functional Relationships(s)
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1 The purpose of this study was to demonstrate the effects of lycopene, the major tomato carotenoid, on the expression of the BRCA1 and BRCA2 genes in three breast tumour cell lines, MCF-7, HBL-100, MDA-MB-231 and the fibrocystic breast cell line MCF-10a. Lycopene BRCA1 DNA repair associated Homo sapiens
2 These preliminary results on the effects of lycopene on the expression of BRCA1 and BRCA2 oncosuppressor genes in breast cancer may reflect cross-talk between the oestrogen and retinoic acid receptor (RAR) pathways. Lycopene BRCA1 DNA repair associated Homo sapiens