Title : [Correlation analysis among expression of ERCC-1, metallothionein, p53 and platinum resistance and prognosis in advanced non-small cell lung cancer].

Pub. Date : 2004 Jul

PMID : 15248926






3 Functional Relationships(s)
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1 The purpose of this study was to evaluate the relationship of the cisplatin sensitivity/prognosis with the expression of excision repair cross complement-1 (ERCC-1), metallothionein (MT), and p53 in the paraffin-embedded tissue of advanced non-small cell lung cancer (NSCLC). Cisplatin ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens
2 The purpose of this study was to evaluate the relationship of the cisplatin sensitivity/prognosis with the expression of excision repair cross complement-1 (ERCC-1), metallothionein (MT), and p53 in the paraffin-embedded tissue of advanced non-small cell lung cancer (NSCLC). Cisplatin ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens
3 CONCLUSION: Whether over-expression of ERCC-1 and MT can be used as a molecular marker of cisplatin resistance in advanced NSCLC patients need further study. Cisplatin ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens