Title : Bronchiolar expression of aquaporin-3 (AQP3) in rat lung and its dynamics in pulmonary oedema.

Pub. Date : 2004 Oct

PMID : 15248066






3 Functional Relationships(s)
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1 In the thiourea group, lung water content increased significantly (vs. controls) with the peak at around 4 h. Semi-quantitative RT-PCR showed that AQP3 mRNA in the thiourea group rose significantly, peaking at around 4-8 h. The expression of AQP1, AQP4, AQP5, ENaC and CFTR mRNA each decreased significantly some time after the peak in lung water content. Water aquaporin 3 (Gill blood group) Rattus norvegicus
2 In the thiourea group, lung water content increased significantly (vs. controls) with the peak at around 4 h. Semi-quantitative RT-PCR showed that AQP3 mRNA in the thiourea group rose significantly, peaking at around 4-8 h. The expression of AQP1, AQP4, AQP5, ENaC and CFTR mRNA each decreased significantly some time after the peak in lung water content. Water aquaporin 3 (Gill blood group) Rattus norvegicus
3 Our results suggest that AQP3 is expressed not only in large airways, but also in bronchioles, and is related to water movement in pulmonary oedema. Water aquaporin 3 (Gill blood group) Rattus norvegicus