Title : Pyrrolidine dithiocarbamate and zinc inhibit proteasome-dependent proteolysis.

Pub. Date : 2004 Aug 1

PMID : 15242777






2 Functional Relationships(s)
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1 Here, we have found that treatment of pyrrolidine dithiocarbamate (PDTC), a zinc ionophore, resulted in the accumulation of several proteasome substrates including p53 and p21 in HeLa cells. pyrrolidine dithiocarbamic acid tumor protein p53 Homo sapiens
2 Here, we have found that treatment of pyrrolidine dithiocarbamate (PDTC), a zinc ionophore, resulted in the accumulation of several proteasome substrates including p53 and p21 in HeLa cells. pyrrolidine dithiocarbamic acid tumor protein p53 Homo sapiens