Title : Structural differences in the DNA binding domains of human p53 and its C. elegans ortholog Cep-1.

Pub. Date : 2004 Jul

PMID : 15242600






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The alpha helix in loop L3 of Cep-1 orients the side chains of two conserved arginines toward DNA; in human p53, both arginines are mutation hotspots, but only one contacts DNA. Arginine centriolin Homo sapiens
2 The alpha helix in loop L3 of Cep-1 orients the side chains of two conserved arginines toward DNA; in human p53, both arginines are mutation hotspots, but only one contacts DNA. Arginine centriolin Homo sapiens