Title : Overexpression of caveolin-1 increases plasma membrane fluidity and reduces P-glycoprotein function in Hs578T/Dox.

Pub. Date : 2004 Jul 30

PMID : 15240128






1 Functional Relationships(s)
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1 Our data demonstrate for the first time that the reduction of the plasma membrane cholesterol level induced by overexpressing caveolin-1 may indirectly inhibit P-gp transport activity by increasing plasma membrane fluidity. Cholesterol phosphoglycolate phosphatase Homo sapiens