Title : Bile acid-induced negative feedback regulation of the human ileal bile acid transporter.

Pub. Date : 2004 Jul

PMID : 15239098






2 Functional Relationships(s)
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1 Antisense mediated knock-down of SHP in Caco-2 cells partially offset the bile acid mediated repression of ASBT promoter activity. Bile Acids and Salts nuclear receptor subfamily 0 group B member 2 Homo sapiens
2 Bile acids induce a negative feedback regulation of human ASBT via an FXR-mediated, SHP-dependent effect upon RAR/RXR activation of ASBT. Bile Acids and Salts nuclear receptor subfamily 0 group B member 2 Homo sapiens