Pub. Date : 2004 Jul 30
PMID : 15234187
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Simvastatin modulates TNFalpha-induced adhesion molecules expression in human endothelial cells. | Simvastatin | tumor necrosis factor | Homo sapiens |
| 2 | In TNFalpha-stimulated HUVEC, simvastatin decreased VCAM-1 and ICAM-1 mRNA levels, inhibited TNFalpha-induced activation of nuclear factor kappaB (NF-kappaB) and enhanced expression of peroxisome proliferator-activated receptor alpha (PPARalpha). | Simvastatin | tumor necrosis factor | Homo sapiens |
| 3 | In TNFalpha-stimulated HUVEC, simvastatin decreased VCAM-1 and ICAM-1 mRNA levels, inhibited TNFalpha-induced activation of nuclear factor kappaB (NF-kappaB) and enhanced expression of peroxisome proliferator-activated receptor alpha (PPARalpha). | Simvastatin | tumor necrosis factor | Homo sapiens |