Title : Biological effects of human gastrin I and II chemically modified at the C-terminal tetrapeptide amide.

Pub. Date : 1992 May-Jun

PMID : 1523164






1 Functional Relationships(s)
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1 Changing the peptide bond between Trp and Leu residues to a -omega(CH2-NH)- bond resulted in a compound which also bound to gastrin receptors (Kd approximately 10 nM) but presented agonist activity on acid secretion in the rat. Tryptophan gastrin Homo sapiens