Title : [A case-control study on the polymorphisms of methylenetetrahydrofolate reductase 1298A-->C and susceptibility of esophageal cancer].

Pub. Date : 2004 Apr

PMID : 15231206






2 Functional Relationships(s)
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1 Individuals having MTHFR 1298C allele and habit of frequent alcohol drinking were at an increased risk of developing EC (adjusted OR = 2.91, 95% CI: 1.20 - 7.08) compared with those with AA genotype and low consumption of alcohol. Alcohols methylenetetrahydrofolate reductase Homo sapiens
2 CONCLUSION: Results in the present study suggested that there was a coordinated effect between MTHFR 1298 genotypes and habits of smoking, alcohol drinking and tea consumption in the development of EC. Alcohols methylenetetrahydrofolate reductase Homo sapiens