Title : Human SCO1 and SCO2 have independent, cooperative functions in copper delivery to cytochrome c oxidase.

Pub. Date : 2004 Sep 1

PMID : 15229189






1 Functional Relationships(s)
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1 We propose a model in which COX17 delivers copper to SCO2, which in turn transfers it directly to the CuA site at an early stage of COX assembly in a reaction that is facilitated by SCO1. Dinuclear Copper Ion synthesis of cytochrome C oxidase 1 Homo sapiens