Title : The involvement of products of the phospholipase pathway in the acute release of tissue-type plasminogen activator from perfused rat hindlegs.

Pub. Date : 1992 Mar 24

PMID : 1521562






1 Functional Relationships(s)
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1 The PAF-induced release of t-PA was inhibited by the cytochrome P-450 mono-oxygenase inhibitors, metyrapone, ketoconazole and SKF 525A and by eicosatetraynoic acid but not by indomethacin or BW 755C, suggesting the involvement of epoxygenase products. Indomethacin PCNA clamp associated factor Rattus norvegicus