Title : Platelet-derived growth factor stimulates membrane lipid synthesis through activation of phosphatidylinositol 3-kinase and sterol regulatory element-binding proteins.

Pub. Date : 2004 Aug 20

PMID : 15213220






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Among them, a cluster of genes involved in fatty acid and cholesterol biosynthesis, including stearoyl-CoA desaturase (SCD), fatty acid synthase, and hydroxymethylglutaryl-CoA synthase (HMGCS), was up-regulated by PDGF after 24 h of treatment, and their expression correlated with increased membrane lipid production. Cholesterol 3-hydroxy-3-methylglutaryl-CoA synthase 1 Homo sapiens
2 Among them, a cluster of genes involved in fatty acid and cholesterol biosynthesis, including stearoyl-CoA desaturase (SCD), fatty acid synthase, and hydroxymethylglutaryl-CoA synthase (HMGCS), was up-regulated by PDGF after 24 h of treatment, and their expression correlated with increased membrane lipid production. Cholesterol 3-hydroxy-3-methylglutaryl-CoA synthase 1 Homo sapiens