Title : Prostaglandin E2 inhibits alveolar macrophage phagocytosis through an E-prostanoid 2 receptor-mediated increase in intracellular cyclic AMP.

Pub. Date : 2004 Jul 1

PMID : 15210817






2 Functional Relationships(s)
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1 Prostaglandin E(2) is a potent lipid mediator of inflammation that effects changes in cell functions through ligation of four distinct G protein-coupled receptors (E-prostanoid (EP)1, EP2, EP3, and EP4). Dinoprostone prostaglandin E receptor 2 Rattus norvegicus
2 Additionally, the EP2 antagonist AH-6809 abrogated the inhibitory effects of both PGE(2) and butaprost. Dinoprostone prostaglandin E receptor 2 Rattus norvegicus