Title : Promising combination therapies with gemcitabine.

Pub. Date : 2004 Apr

PMID : 15199526






2 Functional Relationships(s)
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1 In breast cancer cell lines that expressed either wild-type p53 (MCF-7) or mutant p53 (MCF-7/Adr), sensitivity to the cytotoxic effects of gemcitabine during a 24-hour incubation was similar (IC(50) values 80 and 60 nmol/L in MCF-7 and MCF-7/Adr, respectively). gemcitabine tumor protein p53 Homo sapiens
2 In breast cancer cell lines that expressed either wild-type p53 (MCF-7) or mutant p53 (MCF-7/Adr), sensitivity to the cytotoxic effects of gemcitabine during a 24-hour incubation was similar (IC(50) values 80 and 60 nmol/L in MCF-7 and MCF-7/Adr, respectively). gemcitabine tumor protein p53 Homo sapiens