Pub. Date : 2004 Jul
PMID : 15199134
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Surprisingly, gamma-H2AX foci were also induced in Ercc1(-/-) cells by MMC treatment. | Mitomycin | ERCC excision repair 1, endonuclease non-catalytic subunit | Homo sapiens |
2 | In Ercc1(-/-) cells, MMC-induced gamma-H2AX foci persisted at least 48 h longer than in wild-type cells, demonstrating that Ercc1 is required for the resolution of cross-link-induced DSBs. | Mitomycin | ERCC excision repair 1, endonuclease non-catalytic subunit | Homo sapiens |
3 | In Ercc1(-/-) cells, MMC-induced gamma-H2AX foci persisted at least 48 h longer than in wild-type cells, demonstrating that Ercc1 is required for the resolution of cross-link-induced DSBs. | Mitomycin | ERCC excision repair 1, endonuclease non-catalytic subunit | Homo sapiens |