Title : Glycated albumin activates PAI-1 transcription through Smad DNA binding sites in mesangial cells.

Pub. Date : 2004 Oct

PMID : 15198928






1 Functional Relationships(s)
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1 Quiescent HMC were exposed to 200 microg/ml bovine serum albumin (BSA) or glycated BSA (Gly-BSA) for 12-72 h. At 24 h, Gly-BSA stimulated TGF-beta1 and PAI-1 mRNA expression in HMC to 1.8 and 3.2 times that in the BSA-treated control cells. Glycine transforming growth factor beta 1 Homo sapiens