Title : Dosage-dependent functions of fatty acid desaturase Ole1p in growth and morphogenesis of Candida albicans.

Pub. Date : 2004 Jun

PMID : 15184585






1 Functional Relationships(s)
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1 Partial repression of MET3p-OLE1 slightly lowered oleic acid levels and decreased membrane fluidity; these conditions permitted growth in the yeast form, but prevented hyphal development in aerobic conditions and blocked the formation of chlamydospores. Oleic Acid stearoyl-CoA 9-desaturase Saccharomyces cerevisiae S288C