Title : The clinical implication and molecular mechanism of preferential IL-4 production by modified glycolipid-stimulated NKT cells.

Pub. Date : 2004 Jun

PMID : 15173890






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1 We demonstrate here that the NKT cell production of IFN-gamma is more susceptible to the sphingosine length of glycolipid ligand than that of IL-4 and that the length of the sphingosine chain determines the duration of NKT cell stimulation by CD1d-associated glycolipids. Sphingosine CD1d molecule Homo sapiens