Title : Phosphorylation and recruitment of Syk by immunoreceptor tyrosine-based activation motif-based phosphorylation of tamalin.

Pub. Date : 2004 Jul 30

PMID : 15173175






1 Functional Relationships(s)
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1 Mutation analysis of tyrosine with phenylalanine in COS-7 cells revealed that paired tyrosines at the ITAM sequence of tamalin are phosphorylated preferentially by c-Src and Fyn, and this phosphorylation can recruit Syk kinase and enables it to be phosphorylated by the Src family kinases. Tyrosine SRC proto-oncogene, non-receptor tyrosine kinase Rattus norvegicus