Title : Spermidine/spermine N1-acetyltransferase overexpression in mice induces hypoactivity and spatial learning impairment.

Pub. Date : 2004 May

PMID : 15159132






1 Functional Relationships(s)
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1 The present work addresses the role of polyamines in learning and general behavior by subjecting transgenic mice overexpressing polyamine catabolic enzyme, spermidine/spermine N(1)-acetyltransferase (SSAT) and their syngenic littermates to neurobehavioral profiling assessment (SHIRPA) and to radial eight-arm maze. Polyamines spermidine/spermine N1-acetyl transferase 1 Mus musculus