Pub. Date : 2004 May 28
PMID : 15158362
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We describe the involvement of poly(ADP-ribose)polymerase 1 and 2 (PARP-1 and -2) and poly(ADP-ribose)glycohydrolase (PARG) in the response of rat germinal cells to the action of the NO donors, 3-morpholino-sydnonimine (SIN-1) and spermine nonoate (SNO). | spermine nitric oxide complex | poly (ADP-ribose) polymerase 1 | Rattus norvegicus |
| 2 | We describe the involvement of poly(ADP-ribose)polymerase 1 and 2 (PARP-1 and -2) and poly(ADP-ribose)glycohydrolase (PARG) in the response of rat germinal cells to the action of the NO donors, 3-morpholino-sydnonimine (SIN-1) and spermine nonoate (SNO). | spermine nitric oxide complex | poly (ADP-ribose) polymerase 1 | Rattus norvegicus |
| 3 | We describe the involvement of poly(ADP-ribose)polymerase 1 and 2 (PARP-1 and -2) and poly(ADP-ribose)glycohydrolase (PARG) in the response of rat germinal cells to the action of the NO donors, 3-morpholino-sydnonimine (SIN-1) and spermine nonoate (SNO). | spermine nitric oxide complex | poly (ADP-ribose) polymerase 1 | Rattus norvegicus |
| 4 | We describe the involvement of poly(ADP-ribose)polymerase 1 and 2 (PARP-1 and -2) and poly(ADP-ribose)glycohydrolase (PARG) in the response of rat germinal cells to the action of the NO donors, 3-morpholino-sydnonimine (SIN-1) and spermine nonoate (SNO). | spermine nitric oxide complex | poly (ADP-ribose) polymerase 1 | Rattus norvegicus |
| 5 | Consistent with the DNA repair seen in primary spermatocytes, both SIN-1 and SNO induced PARPs activation in these cells. | spermine nitric oxide complex | poly (ADP-ribose) polymerase 1 | Rattus norvegicus |
| 6 | In the case of SIN-1, there was an immediate but transient response while SNO induced a delayed but more sustained increase in PARPs activity. | spermine nitric oxide complex | poly (ADP-ribose) polymerase 1 | Rattus norvegicus |
| 7 | Chronic exposure of spermatocytes to SIN-1 and SNO, however, committed the cells to apoptosis, which coincided with proteolysis of PARP-1. | spermine nitric oxide complex | poly (ADP-ribose) polymerase 1 | Rattus norvegicus |