Title : CD22 attenuates calcium signaling by potentiating plasma membrane calcium-ATPase activity.

Pub. Date : 2004 Jun

PMID : 15133509






4 Functional Relationships(s)
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Compound Name
Protein Name
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1 CD22 attenuates calcium signaling by potentiating plasma membrane calcium-ATPase activity. Calcium CD22 molecule Homo sapiens
2 We report here that CD22 augments calcium efflux after B cell receptor crosslinking. Calcium CD22 molecule Homo sapiens
3 CD22 cytoplasmic tyrosine residues were required for association with PMCA and enhancement of calcium efflux. Calcium CD22 molecule Homo sapiens
4 Thus, SHP-1 and PMCA provide a mechanism by which CD22, a tissue-specific negative regulator, can affect calcium responses. Calcium CD22 molecule Homo sapiens