Title : Polyphenol, an extract of green tea, increases culture recovery rates of isolated islets from nonhuman primate pancreata and marginal grade human pancreata.

Pub. Date : 2004

PMID : 15129760






2 Functional Relationships(s)
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1 RT-PCR and Western blot analysis of the islets indicated that Bcl-2 levels increased by 2.5-fold and BAX levels decreased by twofold in cultures supplemented with polyphenol. Polyphenols BCL2 associated X, apoptosis regulator Homo sapiens
2 This resulted in BAX/Bcl-2 ratios that were lower in polyphenol-supplemented cultures than with control cultures. Polyphenols BCL2 associated X, apoptosis regulator Homo sapiens