Title : Lobeline analogs with enhanced affinity and selectivity for plasmalemma and vesicular monoamine transporters.

Pub. Date : 2004 Sep

PMID : 15121762






1 Functional Relationships(s)
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1 Lobelane and ketoalkene were 5-fold more potent (Ki = 0.92 and 1.35 microM, respectively) than lobeline (Ki = 5.46 microM) in inhibiting [3H]methoxytetrabenazine binding to VMAT2 in vesicle preparations. Lobeline solute carrier family 18 member A2 Homo sapiens