Title : Multimeric tyrosine sulfate acts as an endothelial cell protectant and prevents complement activation in xenotransplantation models.

Pub. Date : 2004 May

PMID : 15099206






1 Functional Relationships(s)
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1 METHOD: By screening with standard complement (CH50) and coagulation assays (activated partial thromboplastin time, aPTT), a conjugate of tyrosine sulfate to a polymer-backbone (sTyr-PAA) was identified as a candidate EC-protectant. tyrosine O-sulfate CH50 Sus scrofa