Title : Ser-249TP53 mutation in tumour and plasma DNA of hepatocellular carcinoma patients from a high incidence area in the Gambia, West Africa.

Pub. Date : 2004 Jun 20

PMID : 15095302






1 Functional Relationships(s)
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1 A selective mutation in TP53 (AGG-->AGT at codon 249, Arg-->Ser) has been identified as a hotspot in HCCs from such areas, reflecting DNA damage caused by aflatoxin metabolites. Aflatoxins tumor protein p53 Homo sapiens