Title : XR5967, a novel modulator of plasminogen activator inhibitor-1 activity, suppresses tumor cell invasion and angiogenesis in vitro.

Pub. Date : 2004 Jan

PMID : 15090742






1 Functional Relationships(s)
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1 XR5967, a diketopiperazine, dose-dependently inhibited the activity of human and murine PAI-1, towards urokinase plasminogen activator (uPA), with IC50 values of 800 nM and 8.3 microM, respectively. Diketopiperazines serine (or cysteine) peptidase inhibitor, clade E, member 1 Mus musculus