Pub. Date : 2004 Mar
PMID : 15089040
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | (-)-Epigallocatechin-3-gallate and hinokitiol reduce melanin synthesis via decreased MITF production. | beta-thujaplicin | melanocyte inducing transcription factor | Homo sapiens |
| 2 | On the other hand, both EGCG and hinokitiol reduced the protein levels of MITF and of tyrosinase, the rate limiting melanogenic enzyme, whereas kojic acid had no effect. | beta-thujaplicin | melanocyte inducing transcription factor | Homo sapiens |
| 3 | These results show that both EGCG and hinokitiol reduce MITF production, and suggest that reduced tyrosinase activity by hinokitiol explains their synergistic effect on melanogenesis. | beta-thujaplicin | melanocyte inducing transcription factor | Homo sapiens |