Pub. Date : 2003 Dec
PMID : 15073572
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | OBJECTIVES: Detection of the antiestrogenic effect of melatonin on various breast cancer cell lines and its dependence of the differential expression of estrogen receptors (ERalpha and ERbeta) and melatonin receptors (mt1 and RZRalpha). | Melatonin | estrogen receptor 1 | Homo sapiens |
2 | Responsiveness to melatonin depended on expression of ERalpha but not on ERbeta. | Melatonin | estrogen receptor 1 | Homo sapiens |
3 | CONCLUSION: The growth of all ERalpha-positive breast cancer cell lines can be inhibited by melatonin. | Melatonin | estrogen receptor 1 | Homo sapiens |