Title : Calbindin-D28k and calcium sensing receptor cooperate in MCF-7 human breast cancer cells.

Pub. Date : 2004 May

PMID : 15067332






2 Functional Relationships(s)
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1 The normalized dose response curves fitting yielded Hill co-efficient values of 4.32+/-0.63 and 1.49+/-0.14 for Ca2+ and neomycin sulfate respectively, thus indicating highly co-operative, 4-5 binding sites for Ca2+ and 1-2 binding site(s) for neomycin sulfate on CaR. Neomycin CXADR pseudogene 1 Homo sapiens
2 The confocal microscopy data, obtained by using a highly sensitive tyramide signal amplification technology for immunofluorescence detection, showed CaR and calbindin-D28k were co-localized when cells were exposed to 200 micro M neomycin sulfate, whereas in control cells there was no co-localization of these two proteins. Neomycin CXADR pseudogene 1 Homo sapiens