Pub. Date : 2004 Jun 11
PMID : 15060082
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TSG-6 modulates the interaction between hyaluronan and cell surface CD44. | Hyaluronic Acid | TNF alpha induced protein 6 | Homo sapiens |
| 2 | Here we show that preincubation of hyaluronan with full-length recombinant TSG-6 or its Link module domain (Link_TSG6) enhances or induces the binding of hyaluronan to cell surface CD44 on constitutive and inducible cell backgrounds, respectively. | Hyaluronic Acid | TNF alpha induced protein 6 | Homo sapiens |
| 3 | Here we show that preincubation of hyaluronan with full-length recombinant TSG-6 or its Link module domain (Link_TSG6) enhances or induces the binding of hyaluronan to cell surface CD44 on constitutive and inducible cell backgrounds, respectively. | Hyaluronic Acid | TNF alpha induced protein 6 | Homo sapiens |
| 4 | Enhancement of CD44-mediated interactions of lymphoid cells with hyaluronan by TSG-6 proteins was seen under conditions of flow at shear forces that occur in post-capillary venules. | Hyaluronic Acid | TNF alpha induced protein 6 | Homo sapiens |
| 5 | Increases in the number of rolling cells were observed on substrates comprising TSG-6-hyaluronan complexes as compared with a substrate containing hyaluronan alone. | Hyaluronic Acid | TNF alpha induced protein 6 | Homo sapiens |
| 6 | The ability of TSG-6 to modulate the interaction of hyaluronan with CD44 has important implications for CD44-mediated cell activity at sites of inflammation, where TSG-6 is expressed. | Hyaluronic Acid | TNF alpha induced protein 6 | Homo sapiens |
| 7 | The ability of TSG-6 to modulate the interaction of hyaluronan with CD44 has important implications for CD44-mediated cell activity at sites of inflammation, where TSG-6 is expressed. | Hyaluronic Acid | TNF alpha induced protein 6 | Homo sapiens |