Title : Endogenous control of cell cycle progression by autocrine transforming growth factor beta in breast cancer cells.

Pub. Date : 2004 Apr 1

PMID : 15059906






1 Functional Relationships(s)
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1 Tetracycline treatment of RII transfectants led to the suppression of p21/waf1/cip1and p27/kip expression, thus, directly demonstrating induction of CDK inhibitors by autocrine TGF-beta leading to growth control of ER(+) breast cancer cells. rii transforming growth factor beta 1 Homo sapiens